| Description and Composition Soft gel capsule of 4 strenghts are available: ATOPICA contains 10 mg, 25 mg, 50 mg or 100 mg Cyclosporine A per capsule. List of excipients: Tocopherol (E-307), iron oxide black (E 172), titanium dioxide (E 171), edible red ink, excip. ad sol.. Properties ATOPICA contains Cyclosporine A (ATCvet code QL04A A) a selective immunomodulator. It is a cyclic polypeptide consisting of 11 amino acids with a molecular weight of 1203 Daltons which acts specifically and reversibly on T-lymphocytes. Cyclosporine has anti-inflammatory and anti-pruritic activities in atopic dermatitis. Cyclosporine acts specifically and reversibly on resting T-lymphocytes and inhibits the antigen-triggered release of lymphokines by activated T-cells. It also inhibits eosinophil recruitment and activation, keratinocyte cytokine production, Langerhans' cell functions, degranulation of mastocytes and therefore release of histamine and pro inflammatory cytokines. Cyclosporine does not depress hemopoiesis and has no effect on the function of phagocytic cells. A prescription is required for this product. Click here for details |
